Congenital cataract following German measles in the mother. 1941.

Congenital cataract following German measles in the mother. 1942. [classical article].

This paper contains abstracts from publications of the late Sir Norman McAlister Gregg, published in 1941 and 1944, in which he demonstrated the association between rubella in pregnancy and defects in the baby. Besides cataract and retinopathy with which ophthalmologists are familiar, there occur deafness, deafmutism, cardiac defects, mental retardation, pulmonary and renal abnormalities and di...

Congenital Anomalies following German Measles in the Pregnant Mother

Congenital Anomalies following German Measles in the Pregnant Mother

Congenital Malformations

The complacency with which congenital anomalies were once interpreted as expressions of faulty inheritance was rudely shaken in 1940. A convincing demonstration had just occurred in Australia that German measles contracted early in pregnancy by the mother may initiate congenital cataract , deafness, or congenital heart disease in the fetus. A great area for medical exploration had opened. To ap...

Diagnosis and treatment of the more common congenital cardiovascular anomalies.

Malformations of the heart are the result of an arrest or defective development at some specific point. These developmental errors may be due to defective genes or to abnormalities in the environment. German measles during early pregnancy is associated with a high incidence of congenital cataracts and congenital heart anomalies. Since malformations of the heart result from localized arrest in d...